Concise, portable, and user-friendly, The Washington Manual® Pulmonary Medicine Subspecialty Consult, Third Edition, provides quick access to essential information on the diagnosis and management of a variety of acute and chronic lung diseases. Edited by Drs. Adam Anderson, Colleen McEvoy, Mary Clare McGregor, and Shail Mehta, this bestselling manual offers state-of-the-art guidance on the physical exam, diagnosis, management, and treatment follow-up for various pulmonary disorders, including COPD, cystic fibrosis, pulmonary infections, and much more. Ideal for pulmonary medicine fellows, internal medicine residents, advanced practice providers, and medical students rotating on pulmonary subspecialty services, the manual is also useful as a first-line resource for internists and other primary care providers.
- Cover
- Title Page
- Copyright
- Contributors
- Department Chair’s Note
- Preface
- Contents
- 1. The Chest Radiograph
- GENERAL PRINCIPLES
- INITIAL ASSESSMENT
- Patient Position and Study Quality
- CXR Views
- GENERAL APPROACH TO CXR INTERPRETATION
- Osseous Structures
- Upper Abdomen
- The Diaphragm
- The Mediastinum
- The Aorta
- The Hila
- The Pleural and Extrapleural Spaces
- Medical Devices
- Lungs
- Final Steps
- COMMONLY USED FINDINGS FOR EVALUATING LUNG DISEASE
- Radiographic Densities
- Radiographic Signs
- Lobar Collapse
- Pneumothorax
- Diffuse Lung Disease
- 2. Chest Computed Tomography
- GENERAL PRINCIPLES
- INITIAL ASSESSMENT
- Ordering a CT
- CT Scans and Protocols
- Preparing the Patient
- GENERAL APPROACH TO CT INTERPRETATION
- Window Levels and Window Width
- Basic Anatomy
- APPROACH FOR READING CHEST CT
- Soft Tissue Window
- Lung Window
- Basic Lung Parenchymal Patterns
- 3. Pulmonary Function Testing
- GENERAL PRINCIPLES
- NORMAL VALUES AND REFERENCE RANGES
- Percent Predicted Method
- The Lower Limit of Normal Method
- STANDARDIZATION OF PULMONARY FUNCTION TESTS
- Acceptability Criteria
- Reproducibility Criteria
- NORMAL PULMONARY FUNCTION TESTS
- Flow–Volume Loops
- FEV1 and FVC
- Lung Volumes
- EVALUATING PULMONARY FUNCTION TEST PATTERNS
- OBSTRUCTIVE VENTILATORY DEFECTS
- Quantifying an Obstructive Ventilatory Defect
- Assessing for Bronchodilator Reversibility
- Determining if Hyperinflation Is Present
- Determining if Air Trapping Is Present
- The Flow–Volume Loop in Obstructive Ventilatory Defects
- UPPER AIRWAY OBSTRUCTION
- Fixed Upper Airway Obstruction
- Variable Upper Airway Obstruction
- RESTRICTIVE VENTILATORY DEFECTS
- The Flow–Volume Loop in Restrictive Ventilatory Defects
- DIFFUSING CAPACITY
- OTHER PULMONARY FUNCTION TESTS
- Maximal Voluntary Ventilation
- Methacholine Challenge Testing
- 4. Fiberoptic Bronchoscopy
- GENERAL PRINCIPLES
- Pre-bronchoscopy Evaluation
- Procedural Medications
- Monitoring
- Technique
- Postprocedure
- DIAGNOSIS
- TREATMENT
- COMPLICATIONS
- 5. Hypoxemic Respiratory Failure
- GENERAL PRINCIPLES
- Definition
- Classification
- Pathophysiology
- Etiology
- Low Mixed Venous Oxygen Content
- DIAGNOSIS
- Clinical Presentation
- Diagnostic Criteria
- TREATMENT
- Oxygen Delivery Devices
- Other Therapies
- MONITORING, PATIENT EDUCATION, AND FOLLOW-UP
- 6. Noninvasive Ventilation
- GENERAL PRINCIPLES
- Definition
- Clinical Application
- CLASSIFICATION
- Continuous Positive Airway Pressure
- Bilevel Positive Airway Pressure
- Average Volume-Assured Pressure Support
- SPECIFIC DISEASE INDICATIONS FOR NONINVASIVE VENTILATION
- Cardiogenic Pulmonary Edema
- Chronic Obstructive Pulmonary Disease
- Postextubation Respiratory Failure
- Chest Wall Deformity and Neuromuscular Disease
- Acute Hypoxemic Respiratory Failure Trauma
- Asthma
- Palliative Noninvasive Ventilation
- INITIATION OF NONINVASIVE VENTILATION
- SPECIAL CONSIDERATIONS AND MONITORING
- 7. Cough
- GENERAL PRINCIPLES
- Classification
- Etiology
- Pathophysiology
- DIAGNOSIS
- Clinical Presentation
- Diagnostic Criteria: Sputum Production
- Differential Diagnosis
- Diagnostic Testing
- TREATMENT
- SPECIAL CONSIDERATIONS
- 8. Asthma
- GENERAL PRINCIPLES
- DIAGNOSIS
- Clinical Presentation
- Diagnostic Testing
- TREATMENT
- Medications
- Nonpharmacologic Therapies
- Lifestyle Modification and Multimorbidity Management
- ACUTE ASTHMA EXACERBATIONS
- Clinical Presentation
- Diagnostic Testing
- Management of Asthma Exacerbations
- 9. Chronic Obstructive Pulmonary Disease
- GENERAL PRINCIPLES
- Definition
- Classification
- Epidemiology
- Pathophysiology
- Risk Factors
- Associated Conditions
- DIAGNOSIS
- Clinical Presentation
- Diagnostic Criteria
- Differential Diagnosis
- Diagnostic Testing
- Diagnostic Procedures
- TREATMENT
- Acute Exacerbations
- Medications
- Other Nonpharmacologic Therapies
- CHRONIC COPD TREATMENT
- Medications
- Other Nonpharmacologic Therapies
- Surgical Management
- Lifestyle/Risk Modification
- PROGNOSIS
- 10. Tobacco and Inhalational Abuse
- GENERAL PRINCIPLES
- Epidemiology
- Pathophysiology
- Associated Conditions
- DIAGNOSIS
- Diagnostic Criteria
- TREATMENT
- Medications
- Other Nonpharmacologic Therapies
- MONITORING/FOLLOW-UP
- PROGNOSIS
- 11. Community-Acquired Pneumonia
- GENERAL PRINCIPLES
- Definition
- Classification
- Epidemiology
- Etiology
- Pathophysiology
- Risk Factors
- Prevention
- DIAGNOSIS
- Clinical Presentation
- Differential Diagnosis
- Diagnostic Testing
- TREATMENT
- Medications
- Other Nonpharmacologic Therapies
- Duration of Antimicrobial Therapy
- Surgical Management
- MONITORING/FOLLOW-UP
- OUTCOME/PROGNOSIS
- 12. Nosocomial Pneumonia
- GENERAL PRINCIPLES
- Definition
- Classification
- Epidemiology
- Etiology
- Pathophysiology
- Risk Factors
- Prevention
- DIAGNOSIS
- Clinical Presentation
- Diagnostic Testing
- TREATMENT
- Medications
- Duration of Therapy
- 13. Mycobacterial Pulmonary Disease
- GENERAL PRINCIPLES
- Latent TB/TBI
- GENERAL PRINCIPLES
- DIAGNOSIS5
- TREATMENT
- Active Pulmonary TB/ Tuberculosis Disease
- DIAGNOSIS
- SPECIAL CONSIDERATIONS
- TREATMENT
- Nontuberculous Pulmonary Disease
- GENERAL PRINCIPLES
- DIAGNOSIS
- TREATMENT
- Mycobacterium Avium Complex Lung Disease
- Mycobacterium abscessus
- Mycobacterium kansasii
- 14. Fungal Pulmonary Infections
- GENERAL PRINCIPLES
- Aspergillosis
- Invasive Pulmonary Aspergillosis
- GENERAL PRINCIPLES
- DIAGNOSIS
- DIAGNOSTIC TESTING
- TREATMENT
- Subacute and Chronic Necrotizing Aspergillosis
- GENERAL PRINCIPLES
- DIAGNOSIS
- DIAGNOSTIC TESTING
- TREATMENT
- Aspergilloma
- GENERAL PRINCIPLES
- DIAGNOSIS
- DIAGNOSTIC TESTING
- TREATMENT
- Allergic Bronchopulmonary Aspergillosis
- GENERAL PRINCIPLES
- DIAGNOSIS
- DIAGNOSTIC TESTING
- TREATMENT
- Blastomycosis
- GENERAL PRINCIPLES
- DIAGNOSIS
- Clinical Presentation
- Diagnostic Testing
- Treatment
- Candidiasis
- GENERAL PRINCIPLES
- Coccidioidomycosis
- GENERAL PRINCIPLES
- DIAGNOSIS
- DIAGNOSTIC TESTING
- TREATMENT
- Cryptococcosis
- GENERAL PRINCIPLES
- DIAGNOSIS
- DIAGNOSTIC TESTING
- TREATMENT
- Fusariosis
- GENERAL PRINCIPLES
- DIAGNOSIS
- TREATMENT
- Histoplasmosis
- GENERAL PRINCIPLES
- DIAGNOSIS
- DIAGNOSTIC TESTING
- TREATMENT
- COMPLICATIONS
- Mucormycosis
- GENERAL PRINCIPLES
- DIAGNOSIS
- DIAGNOSTIC TESTING
- TREATMENT
- Pneumocystis Pneumonia
- GENERAL PRINCIPLES
- DIAGNOSIS
- DIAGNOSTIC TESTING
- TREATMENT
- 15. Viral Respiratory Infections
- GENERAL PRINCIPLES
- Classification in the Normal Host
- Respiratory Virus Infections in Special Adult Populations
- Prevention
- Diagnosis
- Treatment
- SPECIAL CONSIDERATIONS: SPECIFIC VIRAL PATHOGENS
- Adenovirus
- Coronaviruses
- Cytomegalovirus
- Herpesviruses: HSV-1, EBV, VZV
- Influenza Virus
- Metapneumovirus54
- Parainfluenza Virus54
- Respiratory Syncytial Virus
- Rhinoviruses and Enteroviruses
- Complications
- 16. Cystic Fibrosis
- GENERAL PRINCIPLES
- Definition
- Epidemiology
- Pathophysiology
- DIAGNOSIS
- Clinical Presentation
- Diagnostic Criteria
- Differential Diagnosis
- Diagnostic Testing
- TREATMENT
- Pulmonary
- Gastrointestinal
- Endocrine and Reproductive
- Lung Transplantation
- SPECIAL CONSIDERATIONS
- COMPLICATIONS
- 17. Hemoptysis
- GENERAL PRINCIPLES
- Definition
- DIAGNOSIS
- Clinical Presentation
- Differential Diagnosis
- Diagnostic Testing
- TREATMENT
- 18. Diffuse Alveolar Hemorrhage
- GENERAL PRINCIPLES
- DIAGNOSIS
- Clinical Presentation
- Differential Diagnosis
- Diagnostic Testing
- TREATMENT
- 19. Pulmonary Vasculitis
- Vasculitis Overview
- GENERAL PRINCIPLES
- Definition
- Classification
- Epidemiology
- DIAGNOSIS
- TREATMENT
- SPECIAL CONSIDERATIONS
- Granulomatosis with Polyangiitis
- GENERAL PRINCIPLES
- DIAGNOSIS
- Clinical Presentation
- Diagnostic Criteria
- Diagnostic Testing
- TREATMENT
- Microscopic Polyangiitis
- GENERAL PRINCIPLES
- DIAGNOSIS
- Clinical Presentation
- Diagnostic Criteria
- Diagnostic Testing
- TREATMENT
- Eosinophilic Granulomatosis with Polyangiitis
- GENERAL PRINCIPLES
- DIAGNOSIS
- Clinical Presentation
- Diagnostic Criteria
- Differential Diagnosis
- Diagnostic Testing
- TREATMENT
- 20. Pulmonary Embolism and Deep Venous Thrombosis
- GENERAL PRINCIPLES
- Definition
- Epidemiology
- Etiology
- Risk Factors
- Pathophysiology
- DIAGNOSIS
- Clinical Presentation
- Differential Diagnosis
- Diagnostic Testing
- RISK STRATIFICATION
- TREATMENT
- General Principles
- Respiratory and Circulatory Support
- Anticoagulation
- PE Response Teams
- Thrombolysis
- Inferior vena cava (IVC) Filters
- Advanced Therapies
- Complications of Therapy
- PROGNOSIS
- MONITORING AND FOLLOW-UP
- 21. Pulmonary Hypertension
- GENERAL PRINCIPLES
- Definition
- Classification
- Epidemiology
- Pathophysiology
- DIAGNOSIS
- Clinical Presentation
- Diagnostic Criteria
- Diagnostic Testing
- Diagnostic Procedures
- TREATMENT
- Treatment of Groups 2–4
- Pharmacologic Therapy for Group 1
- Other Nonpharmacologic Therapies
- Surgical Management
- Lifestyle/Risk Modification
- REFERRAL
- MONITORING/FOLLOW-UP
- OUTCOME/PROGNOSIS
- 22. Pleural Diseases
- GENERAL PRINCIPLES
- Definition
- Epidemiology
- Etiology
- Pathophysiology
- Risk Factors
- DIAGNOSIS
- Clinical Presentation
- Diagnostic Criteria
- Differential Diagnosis
- Diagnostic Testing
- TREATMENT
- Medications
- Other Nonpharmacologic Therapies
- Surgical Management
- SPECIAL CONSIDERATIONS
- COMPLICATIONS
- REFERRAL
- 23. Sleep-Disordered Breathing
- GENERAL PRINCIPLES
- Definitions1
- Classification
- Epidemiology
- Etiology
- Pathophysiology
- Risk Factors
- Prevention
- Associated Conditions
- DIAGNOSIS
- Clinical Presentation
- Diagnostic Criteria
- Differential Diagnosis
- Diagnostic Testing
- Diagnostic Procedures
- TREATMENT
- Medications
- Nonpharmacologic Therapies
- Lifestyle/Risk Modification
- 24. Interstitial Lung Disease
- GENERAL PRINCIPLES
- Classification and Epidemiology
- Etiology and Pathogenesis
- DIAGNOSIS
- Overview of Diagnosis
- Clinical Presentation
- Diagnostic Testing
- Imaging
- Lung Sampling
- Diagnostic Features of Selected Diseases
- TREATMENT
- Overview of Treatment
- Immunosuppressive Therapy
- Other Pharmacologic Therapies
- Nonpharmacologic Therapies
- Advance Care Planning and Palliative Care
- CONCLUSIONS
- 25. Occupational Lung Disease
- INTRODUCTION
- Asbestos-Associated Lung Disease
- GENERAL PRINCIPLES
- DIAGNOSIS
- Coal Dust-Associated Pulmonary Disease
- GENERAL PRINCIPLES
- DIAGNOSIS
- Silica-Associated Lung Disease
- GENERAL PRINCIPLES
- DIAGNOSIS
- Workplace- and Environment-Associated Bronchial Reactivity
- GENERAL PRINCIPLES
- DIAGNOSIS
- TREATMENT
- Hypersensitivity Pneumonitis
- General Principles
- DIAGNOSIS
- Diagnostic Testing
- TREATMENT
- Toxic Lung Injury
- Silo Filler’s Disease
- CHRONIC BERYLLIUM DISEASE
- 26. Antineoplastic Therapy–Induced Pulmonary Disease
- GENERAL PRINCIPLES
- Classification and Epidemiology
- Pathophysiology
- Risk Factors
- DIAGNOSIS
- Clinical Presentation
- History
- Diagnostic Criteria
- Differential Diagnosis
- Imaging
- Diagnostic Procedures
- TREATMENT
- Medications
- OUTCOME/PROGNOSIS
- 27. Solitary Pulmonary Nodule
- GENERAL PRINCIPLES
- DIAGNOSIS
- Clinical Presentation
- Differential Diagnosis
- Diagnostic Testing
- Further Evaluation of the SPN
- TREATMENT
- 28. Lung Transplantation
- GENERAL PRINCIPLES
- DONOR AND CANDIDATE SELECTION
- Indications and Timing of Referral by Diagnosis
- Recipient Selection and Organ Allocation
- Donor Selection
- Surgical Considerations
- TREATMENT
- Immunosuppressive Therapy
- Specific Agents
- COMPLICATIONS
- Hyperacute Rejection
- Acute Rejection
- Antibody-Mediated Rejection
- Chronic Rejection
- Infection in the Lung Transplant Patient
- Posttransplant Lymphoproliferative Disorder
- Other Complications
- OUTCOMES
- Index