Antimicrobial Resistance: Underlying Mechanisms and Therapeutic Approaches

Antimicrobial resistance (AMR) is a global public health threat that  needs immediate attention and action from the scientific community. This  book compiles and presents the latest and most important aspects of  AMR, including the biology involved, its persistence and spread, and  novel approaches to tackle this threat. The book first describes the  mechanisms and spread of AMR, and then discusses the various approaches  and strategies for combating it.

Important topics include,  microbial pathogenesis, AMR traits and major mechanisms underlying  drug-resistance and the emerging strategies and technologies for  combating AMR. Emphasis has been given on current developments about  natural products including potent phyto-molecules, antimicrobial  peptides and endophytes effective against the drug-resistant microbes  and target the main drug-resistance determinants (efflux pumps,  biofilms, quorum sensing, plasmids, etc.) in these bacterial pathogens.  Other exciting topics include applications of nanomaterials in tackling  AMR and CRISPR-Cas based precise sequence-specific antimicrobials.

This  informative book is meant for students and researchers in basic and  medical microbiology and biotechnology. It is also useful to public  health professionals and industry experts involved in AMR research and  related drug-designing.