Current Drug Synthesis

The latest entry in the widely read Drug Synthesis series

In  Current Drug Synthesis, accomplished medicinal chemist and researcher  Dr. Jie Jack Li and 27 expert coauthors deliver an authoritative and  comprehensive discussion of the medicinal chemistry of current drugs, as  well as the cutting-edge science involved in their synthesis. The book  demystifies the process of modern drug discovery for both industry  practitioners and students, while capturing the state-of-the-art  techniques used to discover some of the most impactful medicines on the  market today.

Covering six different disease areas – including  infectious disease, cancer, cardiovascular and metabolic disease, the  central nervous system, anti-inflammatory disease, and a miscellaneous  section – the book explores 18 different drugs before concluding with  chapters on computational drug discovery and peptide drugs.

Each  chapter includes coverage of background material on a relevant drug  class or disease indication and key aspects of drug discovery, including  structure-activity relationships, pharmacokinetics, drug metabolism,  efficacy, and safety.

Readers will also find:
Thorough  introductions to drugs for infectious diseases, including relebactam,  vaborbactam, and baloxavir marboxilIn-depth treatments of  cancer-treating drugs, including darolutamide, venetoclax, and  osimertinib Comprehensive explorations of central nervous system drugs,  including zuranolone and risdiplam Extensive discussions of  computational drug discovery and peptide drugs
Perfect for medicinal,  organic, synthetic, and process chemists, Current Drug Synthesis will  also earn a place in the libraries of research scientists working in  lead optimization and process development, as well as graduate students  studying organic chemistry, heterocyclic chemistry, or medicinal  chemistry.