Modelling of Complex Signals in Nerves

This book describes fundamental physical principles, together with their  mathematical formulations, for modelling the propagation of signals in  nerve fibres. Above all, it focuses on the complex  electro-mechano-thermal process that produces an ensemble of waves  composed of several components, besides the action potential. These  components include mechanical waves in the biomembrane and axoplasm,  together with the temperature change. Pursuing a step-by-step approach,  the content moves from physics and mathematics, to describing the  physiological effects, and finally to modelling the coupling effects.  The assumptions and hypotheses used for modelling, as well as selected  helpful concepts from continuum mechanics, are systematically explained,  and the modelling is illustrated using the outcomes of numerical  simulation. The book is chiefly intended for researchers and graduate  students, providing them with a detailed description of how to model the  complex physiological processes in nerve fibres