Phylogenomics: Foundations, Methods, and Pathogen Analysis

Phylogenomics: Foundations, Methods, and Pathogen Analysis offers a deep overview of phylogenomics as a field, compelling recent developments, and detailed methods and approaches for conducting new research. Early chapters introduce phylogenomic analysis of viruses and bacteria, deciphering bacterial outbreaks, and evolution of drug resistance and virulence, with a second section on methods offering instruction in tools for SNP calling and dealing with big datasets, use of Bayesian approach in molecular epidemiology, bacterial evolution modeling and evolutionary reconstruction in the presence of mosaic sequences. Part 3 offers various examples of phylogenomic analysis across medically significant bacteria and viruses, including Yersinia pestis, Salmonella, Mycobacterium tuberculosis, HIV-1, measles virus as well as ancient pathogens research.

• Offers a full overview of phylogenetics and phylogenomics, from its foundations to methods and specialized case studies
• Presents methodologies and algorithms for phylogenomic research studies and analyzes medically significant microorganisms
• Considers examples of phylogenomic analysis across a range of medically significant pathogens
• Includes chapter contributions from leading international experts