Trace Elements in Brain Health and Diseases

This book reviews the role of trace elements in brain development,  function, metabolism, and neurodegenerative disorders. It explores the  molecular mechanisms of the effects of trace elements on  metabolic  pathways, mitochondrial nutrients, neurodegeneration, Central Nervous  System (CNS) disorders, cell signaling, and neuronal functions. The book  also discusses transport mechanisms of trace elements within CNS and  their impact on neurotransmitter biology. Further, it examines the  deleterious effects due to dyshomeostasis of trace elements in the  central nervous system (CNS), resulting in damage to neurons and glial  cells through the generation of reactive oxygen species and oxidative  stress turn leading to neurodegeneration and neurological dysfunction.  The book also explores the putative role of trace element deficiency in  psychiatric disorders, including depression, and the imbalance of trace  elements on neuronal genomic stability.